'NCCS has achieved great progress in discovery of first long non-coding RNA': Dr Shekhar Mande

'NCCS has achieved great progress in discovery of first long non-coding RNA': Dr Shekhar Mande This dogma states that precise regions of the DNA (genes) code for proteins thru an intermediate RNA molecule. Shiras determined that different varieties of RNA molecules additionally exist, which do no longer code for proteins, hence beginning the sphere of lengthy non-coding RNAs. Dr. Arvind Sahu's paintings on how viruses overcome the human host's immune response has also been path-breaking. His paintings, which sheds light at the mechanisms of immune evasion via viruses, can consequently assist design extra green healing strategies. Several corporations are engaged in cancer, diabetes and different studies. What are the today's traits? One of the middle research strengths of NCCS is cancer biology. Different groups right here have addressed many fundamental questions in this vicinity. Dr Sharmila Bapat's group has shown that the ovarian cancer tissue consists of no longer simply one cell kind, however that the tumor mass is a heterogenous series of cells. This underscores the want to goal some of these one of a kind cell sorts while designing healing procedures against ovarian most cancers. Dr. Gopal Kundu has developed molecules and their nano formulations, which may be used to combat towards breast cancer. These findings have also been acknowledged by using the National Innovation Foundation. Technologies advanced at NCCS have been commercialised. What are the important thing ones inside the marketplace? We have been interfacing with enterprise. Preparations from fenugreek (methi) seeds, which seem to assist mitigate obesity and diabetes, were commercialised. Some of the first few technologies that had been advanced at NCCS including the cryopreservation of bone marrow cells and big-scale expansion of human pores and skin lifestyle for the remedy of burns had been additionally transferred to public hospitals. Many more findings and technologies of NCCS had been patented, and a few are within the manner of commercialisation. What are the challenges faced by using scientists in bringing studies from the laboratory to the sufferers? The fundamental challenges which are faced via scientists is that discoveries as a consequence of fundamental studies performed at the laboratory aren't at a degree that may be without problems taken up by way of the enterprise for massive-scale commercialisation. This hole among the two ends needs to be stuffed, for successful commercialisation of technology developed with the aid of the scientists. Not being an exception to this, NCCS too has confronted this task. Recognising that one of the capacity ways for filling this hole is to promote begin-ups, we've got taken up the mantle of moving on this path. NCCS changed into currently provided the distinguished furnish to set up an ATAL Incubation Centre, which proposes to sell start-ups, a few of which can be in all likelihood to take the discoveries made at NCCS toward similarly commercialisation. Space has been a problem for numerous scientific institutes. How has NCCS tackled it? Partnering with suitable hospitals on the only hand, and with the biotech enterprise on the alternative, could allow NCCS to make a much bigger contribution to the society. This could contain expansion in lots of approaches, simultaneously requiring lots more area than the ten acres of land presently being utilized by NCCS, which has been made available by way of Pune University. What are the centre's future plans? One of the major projects of NCCS is to coordinate with the Indian Human Microbiome Initiative. This mission is probable to be similar in value to the Mars project or the Moon mission. This assignment attempts to sample 20,000 Indians from awesome ethnic backgrounds for the bacterial populations that they host on and of their bodies. It can be noted right here that every one humans host extra bacterial cells than their own cells. These bacteria play important roles in human physiology and the general fitness of an person. However, the spectrum of those micro organism varies widely with ethnic backgrounds, meals conduct, etc. This necessitates studies which might be applicable to the Indian populace. The Indian Human Microbiome Initiative, with a view to be spearheaded through NCCS inside the coming years, will mainly address this requirement and help offer beneficial information pertinent to the health of the Indian populace. NCCS additionally plans to installation a number one mobile banking, with a view to function a repository of primary cellular cultures. This serves as better laboratory fashions to have a look at human diseases, being closer in function to the human frame than the traditionally-used cellular strains. Dailyhunt https://en.gravatar.com/kizansjaan